无药可救病入膏肓
[wú yào kĕ jiù bìng rù gāo huāng]
'There is no medicine to cure my disease which becomes incurable.' It humorously indicates a hopeless situation that it has become very serious, almost impossible to save or recover. Perhaps expressing despair, helplessness, self-depreciation about one's own bad habit or a bad state of affairs around.