至此终年锦瑟无端
[zhì cĭ zhōng nián jĭn sè wú duān]
'To this point, throughout the year the decorated stringed instrument plays without reason'. It refers to unexplained melancholic emotions that linger for an entire year, drawing a poetic imagery similar to music that no one listens to and no one understands. This evokes a sense of loneliness and melancholy.