开始的尽头是结束熟悉的尽头是陌生
[kāi shĭ de jĭn tóu shì jié shù shú xī de jĭn tóu shì mò shēng]
'Start end in the end is the finish familiar ends up strange (beginning and familiarity always ends up turning strange)', indicating the irony or uncertainty in relationships and changes over time.