今生今世姐与你无缘
[jīn shēng jīn shì jiĕ yŭ nĭ wú yuán]
This lifetime and this era, sisters will have no connection with you. Here the person uses 'sister' to represent a female speaking out the fact of not having any chance (probably romantic) with 'you', expressing decisiveness or disappointment in the current interpersonal situation